Human Genetics and Disease Discovery

In honor of David Botstein, PhD, Ronald W. Davis PhD, and David S. Hogness, PhD for their seminal contributions to the concepts and methods of creating a genetic map in the human, and of positional cloning, leading to the identification of thousands of human disease genes and ushering in the era of human genetics.

PROGRAM

Opening Remarks

Jeffrey S. Flier, MD
Dean of the Faculty of Medicine, Harvard University

Moderated by

Stephen Elledge, PhD
Gregor Mendel Professor of Genetics and Medicine, Harvard Medical School and Brigham and Women’s Hospital
Investigator, Howard Hughes Medical Institute

Fred Winston, PhD
John Emory Andrus Professor of Genetics, Harvard Medical School

Remarks and Reflections

Ronald W. Davis, PhD
Professor of Biochemistry and Genetics; Director, Stanford Genome Technology Center, Stanford University School of Medicine

David Botstein, PhD
Anthony B. Evnin Professor of Genomics, Princeton University

Invited Speakers

Where Is the Rest of the Human Genome?
Steven McCarroll, PhD
Assistant Professor, Department of Genetics, Harvard Medical School
Director of Genetics, Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard

Human Genetic Variation and Common Disease
David Altshuler, MD, PhD
Professor of Genetics and of Medicine, Harvard Medical School and Massachusetts General Hospital
Deputy Director and Chief Academic Officer, The Broad Institute of MIT and Harvard

Rare Variants, Therapeutic Targets, and the Future of Medicine
Richard P. Lifton, MD, PhD
Sterling Professor and Chair, Department of Genetics; Professor of Genetics,
Internal Medicine & Molecular Biophysics & Biochemistry, Yale University School of Medicine
Investigator, Howard Hughes Medical Institute